Aug 6, 2012
In animal cells, the nuclear lamina keeps nuclear pore complexes evenly distributed throughout the nuclear envelope. Steinberg et al. reveal that fungi, which lack nuclear laminae, prevent their nuclear pores from clustering by moving them around on cytoskeletal tracks, a process that also helps to organize fungal chromosomes and optimize nucleocytoplasmic transport. This biosights episode presents the paper by Steinberg et al. from the August 6, 2012, issue of the Journal of Cell Biology and includes an interview with senior author Gero Steinberg (University of Exeter, UK). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.
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