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May 12, 2014

Phosphoinositides get cells in shape

Early Drosophila embryos undergo 13 rounds of rapid nuclear division before enclosing each nucleus into an individual, membrane-bound cell. Reversi et al. describe how the phosphoinositides PI(4,5)P2 and PI(3,4,5)P3 control the resulting cell shapes by coordinating actomyosin...