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biosights

Nov 29, 2010

Centrosome positioning is thought to be important for both neuronal migration and axonogenesis. To investigate centrosome dynamics in vivo, Distel et al. develop a new method to simultaneously visualize multiple subcellular compartments...


Nov 1, 2010

Most migrating cells place their centrosome in front of the nucleus, facing the direction in which the cell is moving. Manneville et al. identify a signaling pathway that moves the centrosome into position by recruiting the motor protein dynein to leading edge microtubules...