Preview Mode Links will not work in preview mode


Aug 29, 2016

Septins step in to promote macropinosome fusion

After they are formed by the closure of membrane ruffles, macropinosomes mature by fusing with each other and with endosomes, before eventually delivering their fluid phase cargo to lysosomes. Dolat and Spiliotis reveal that septin filaments promote macropinosome...

Aug 1, 2016

The midbody enables ciliogenesis

Fibroblasts initiate ciliogenesis inside the cell, but polarized epithelial cells form a primary cilium at the apical cell surface through a mechanism that is largely uncharacterized. BernabĂ©-Rubio et al. reveal that, in polarized MDCK cells, a remnant of the cytokinetic midbody moves...